Innate and acquired immunity. Cells and organs of the immune system. Antibodies and antigens. Major histocompatibility complex. Antigen processing and presentation to T lymphocytes. Antigen receptors and accessory molecules of T lymphocytes. Maturation and activation of lymphocytes. Generation of antibody diversity. Immunological tolerance. Cytokines. Complement. Effector mechanisms of immune responses. Immune response to infection with emphasis on the pathogenic mechanisms of clinically relevant microbes. Immune response in cancer. Transplantation immunology and immunosuppression. Autoimmunity. Immundeficiencies. Vaccination.